Cerebrospinal fluid Aβ42 levels and APP processing pathway genes in Parkinson's disease.
Identifieur interne : 000300 ( Main/Exploration ); précédent : 000299; suivant : 000301Cerebrospinal fluid Aβ42 levels and APP processing pathway genes in Parkinson's disease.
Auteurs : Lynn M. Bekris [États-Unis] ; Debby W. Tsuang [États-Unis] ; Elaine R. Peskind [États-Unis] ; Chang E. Yu [États-Unis] ; Thomas J. Montine [États-Unis] ; Jing Zhang [États-Unis] ; Cyrus P. Zabetian [États-Unis] ; James B. Leverenz [États-Unis]Source :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2015.
Abstract
Of recent interest is the finding that certain cerebrospinal fluid (CSF) biomarkers traditionally linked to Alzheimer's disease (AD), specifically amyloid beta protein (Aβ), are abnormal in PD CSF. The aim of this exploratory investigation was to determine whether genetic variation within the amyloid precursor protein (APP) processing pathway genes correlates with CSF Aβ42 levels in Parkinson's disease (PD).
DOI: 10.1002/mds.26172
PubMed: 25808939
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Of recent interest is the finding that certain cerebrospinal fluid (CSF) biomarkers traditionally linked to Alzheimer's disease (AD), specifically amyloid beta protein (Aβ), are abnormal in PD CSF. The aim of this exploratory investigation was to determine whether genetic variation within the amyloid precursor protein (APP) processing pathway genes correlates with CSF Aβ42 levels in Parkinson's disease (PD).</div>
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<tree><country name="États-Unis"><region name="Ohio"><name sortKey="Bekris, Lynn M" sort="Bekris, Lynn M" uniqKey="Bekris L" first="Lynn M" last="Bekris">Lynn M. Bekris</name>
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<name sortKey="Leverenz, James B" sort="Leverenz, James B" uniqKey="Leverenz J" first="James B" last="Leverenz">James B. Leverenz</name>
<name sortKey="Montine, Thomas J" sort="Montine, Thomas J" uniqKey="Montine T" first="Thomas J" last="Montine">Thomas J. Montine</name>
<name sortKey="Peskind, Elaine R" sort="Peskind, Elaine R" uniqKey="Peskind E" first="Elaine R" last="Peskind">Elaine R. Peskind</name>
<name sortKey="Tsuang, Debby W" sort="Tsuang, Debby W" uniqKey="Tsuang D" first="Debby W" last="Tsuang">Debby W. Tsuang</name>
<name sortKey="Yu, Chang E" sort="Yu, Chang E" uniqKey="Yu C" first="Chang E" last="Yu">Chang E. Yu</name>
<name sortKey="Zabetian, Cyrus P" sort="Zabetian, Cyrus P" uniqKey="Zabetian C" first="Cyrus P" last="Zabetian">Cyrus P. Zabetian</name>
<name sortKey="Zhang, Jing" sort="Zhang, Jing" uniqKey="Zhang J" first="Jing" last="Zhang">Jing Zhang</name>
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